Monday 6 August 2018

Scientists study the effects drugs have on the brain and behavior. They use this information to develop programs for preventing drug use and for helping people recover from addiction.

The delivery of drug at right time to right target is an essential requirement for treatment of cancer. The advances in understanding the molecular biology of cancer and novel drug delivery systems have satisfied these requirements. The newer approaches do not only supplement the conventional chemotherapy and radiotherapy but also aim to prevent the drug resistance. The proposed review focuses light on novel formulation strategies like microemulsions, nanoemulsions, microspheres, liposomes and device strategies like inhalation devices, blunt needle injection for cancer.  The drugs are delivered to the entire body via the blood circulation and only a small proportion of the total dose reaches the site where it is required  The high doses often required to achieve the requisite therapeutic effect at the site of action has the potential to cause toxic side effects  Acquisition of Multi Drug Resistance  Rapid clearance by Reticuloendothelial system  Hydrophobicity of the anticancer drugs All the above problems can be overcome by advanced drug delivery systems which are clas-sified as under :  Formulation based approach

No comments:

Post a Comment

Medicinal Organic Chemistry

It is an interdisciplinary research field which incorporates different branches of hashtag # chemistry and hashtag # biology for hashtag ...